This month, Academic Press has published my book, Evolution’s Clinical Guidebook: Translating Ancient Genes Into Precision Medicine. The premise of this book is that modern medicine is based, in one way or another, on an understanding of evolutionary processes. If evolution were a fabrication, then we would not be able to make any sense of the genomic data that is pouring out of research laboratories. We would not be able to design rational, cost effective, screening protocols to test the effectiveness of new drugs. We would not be able to identify the human sub-populations that will benefit from gene-targeted therapies. We would not be able to find the cause of rare diseases, and we would not be able to apply such knowledge to the treatment of common diseases. Without evolution, we would not understand how cancer develops, or how we might intervene in the process. Basically, without evolution, the fledgling field of precision medicine would wither and die, and we would lose our opportunity to prevent, diagnose, and treat the diseases that account for the bulk of morbidity and mortality in humans and in animals. This book demonstrates, through hundreds of examples, that modern medicine is built on the theory of evolution.
This book is available from Amazon or from the publisher's website. If you are fortunate enough to have full institutional access to ScienceDirect, you can download chapters at no cost.
Jules Berman
key words: evolution, precision medicine, genetics, rare disease, clinical genetics, bioinformatics, evo-devo, Jules J. Berman, Ph.D., M.D.
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